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Scientists have found that sperm DNA from the testicles of many infertile men is as good as that of ejaculated sperm of fertile men. This may explain a major cause of male infertility and opens the possibility of using sperm taken directly from the testicles of these men; to overcome their infertility.
In the largest such study so far undertaken, US researchers have shown that testosterone replacement slows the recurrence of prostate cancer in low-risk patients. This may call into question the general applicability of Nobel-Prize winning hormonal prostate treatment. The work is presented at the European Association of Urology congress in Barcelona.
Millions of people work nights, but increasingly scientists are finding that night work is associated with health problems. Now a group of Italian scientists has found that nightshift workers also need to pee more, leading to a deteriorating quality of life for many workers, including care workers. This is also true of younger subjects, who would not normally be expected to report an overactive bladder. This work is reported at the European Association of Urology Congress in Barcelona.
Scientists have found that men with high neuroticism – between a quarter and a fifth of men in developed countries – are significantly more likely to suffer from adverse events such as erectile dysfunction and incontinence, which may put their recovery from prostate cancer surgery at risk. The researchers say that this means cancer teams may need to consider testing for personality types to try to ensure that patients being treated for prostate cancer receive the best care. This work is presented at the European Association of Urology Congress in Barcelona.
Research shows that experiencing menopause before the age of 45 is associated with a higher risk of bladder cancer. This higher risk was notable if the woman is a smoker. The study, which looked at health outcomes of more than 220,000 US Nurses, is presented at the European Association of Urology congress in Barcelona. Bladder cancer is the 6th most common cancer diagnosed in Europe*. It is more common in men than in women, but women are more likely to suffer from advanced bladder cancer and are less likely to survive than men. Around 27,000 European women and 19,000 US women are diagnosed with bladder cancer each year.
Many wives of advanced prostate cancer sufferers feel that their lives are being undermined by their husband’s illness, with nearly half reporting that their own health suffered. In addition a focus subgroup has revealed that many feel isolated and fearful, and worry about the role change in their lives as their husband’s cancer advances. This study, developed with the wives of men with metastatic prostate cancer who were being treated with hormone therapy, is amongst the first carried out on how prostate cancer affects the partners of sufferers. It was presented yesterday at the EAU conference in Copenhagen.
A large international study has shown that an MRI scan can reduce the number of invasive prostate biopsies by up to 28%. The PRECISION1 trial shows that using MRI to target prostate biopsies leads to more of the harmful prostate cancers, and fewer harmless cancers being diagnosed. Given that more than a million men in Europe undergo a prostate biopsy every year, the authors believe that this work could change clinical practice. The results are presented at the European Association of Urology Congress in Copenhagen, with simultaneous publication in the New England Journal of Medicine2.
Scientists have found that a drug connected with fat regulation prevents the formation of kidney stones in mice. This early work opens the possibility of developing drugs which may help prevent kidney stones in at-risk individuals. The work is presented at the European Association of Urology Conference in Copenhagen.
Scientists have developed a transgender-specific questionnaire, which confirms for the first time that gender surgery significantly improves quality of life for the majority of patients. The study shows that 80% of male-to-female patients perceived themselves as women post-surgery. However, the quality of life of transgender individuals is still significantly lower than the general population.
Chinese scientists and clinicians have developed a learning artificial intelligence system which can diagnose and identify cancerous prostate samples as accurately as any pathologist. This holds out the possibility of streamlining and eliminating variation in the process of cancer diagnosis. It may also help overcome any local shortage of trained pathologists. In the longer term, it may lead to automated or partially-automated prostate cancer diagnosis.