ERN eUROGEN Webinar: Hirschsprung disease: basic principles of pathology

In this webinar, the pathophysiology of Hirschsprung disease will be discussed in order to provide a deeper inside and understanding of the mechanisms of the disease.

Wed, 28 Sep 2022
Organiser ERN eUROGEN
Location Virtual

This webinar will be presented by Dr. Roxana Rassouli-Kirchmeier from the Amalia Children’s Hospital in Nijmegen and Dr. Thomas Menter from the Institute of Medical Genetics and Pathology at University Hospital Basel.

The presenters will discuss their approach to an adequate work-up of biopsies taken to confirm or rule out this diagnosis. This approach is based on enzyme-histochemistry in order to evalute the presence of neurons of the enteric nerve system and to evaluate the parasympathetic innervation. In addition, they will demonstrate the respective findings by performing live microscopy of illustrative cases.
Finally, Dr. Rassouli-Kirchmeier will discuss the surgical techniques to obtain optimal biopsies.

The ARM webinar series covers all aspects of paediatric colorectal surgery, in particular (congenital) anorectal malformations. They are joint presentations between ERNs eUROGEN and ERNICA, and are supported by ARM-Net.

ERN eUROGEN is the ERN for rare and complex urorectogenital diseases and conditions. For more information, visit

ERN ERNICA is the ERN for rare Inherited and Congenital (digestive and gastrointestinal) Anomalies. For more information, visit

The ARM-Net Consortium is a group of professionals and patient representatives that aim to exchange data and knowledge to improve clinical care and to perform research on congenital anorectal malformations. For more information, visit

Please note that:
- Our webinars are not currently accredited.
- All webinars are recorded and subsequently shared via both our YouTube channel and GoToWebinar platform.