Male Infertility

Full Text Guidelines Summary of Changes Scientific Publications & Appendices Pocket Guidelines Archive Panel

2019

The 2019 Male Infertility Guidelines have not been updated since 2018. This is the current version.

2018

For the 2018 edition of the EAU Male Infertility Guidelines, the Guidelines Office have transitioned to a modified GRADE methodology. For each recommendation within the guidelines there is an accompanying online strength rating form which addresses a number of key elements namely:

  1. the overall quality of the evidence which exists for the recommendation;
  2. the magnitude of the effect (individual or combined effects);
  3. the certainty of the results (precision, consistency, heterogeneity and other statistical or study related factors);
  4. the balance between desirable and undesirable outcomes;
  5. the impact of patient values and preferences on the intervention;
  6. the certainty of those patient values and preferences.

These key elements are the basis which panels use to define the strength rating of each recommendation. The strength of each recommendation is determined by the balance between desirable and undesirable consequences of alternative management strategies, the quality of the evidence, and nature and variability of patient values and preferences. The strength of each recommendation is represented by the words ‘strong’ or ‘weak’.

 

In addition, new and relevant evidence has been identified, collated and appraised through a structured assessment of the literature. A broad and comprehensive literature search, covering all sections of the Male Infertility Guidelines was performed. The search was limited to studies representing high levels of evidence, i.e. systematic reviews with meta-analysis, randomised controlled trials (RCTs), and prospective non-randomised comparative studies, published in the English language. Additional references and text updates have been incorporated throughout the text as a result of this search.

2017

For the 2017 Male Infertility Guidelines, new and relevant evidence has been identified, collated and appraised through a structured assessment of the literature. A broad and comprehensive literature search, covering all sections of the Male Infertility Guidelines was performed. The search was limited to studies representing high levels of evidence, i.e. systematic reviews with meta-analysis, randomised controlled trials (RCTs), and prospective non-randomised comparative studies, published in the English language. Additional references and text updates have been incorporated throughout the text as a result of this search.

2016

For the 2016 Guidelines, new data from a broad scope search have been included in the text. No significant changes were made to the recommendations.

2015

For the 2015 Guidelines, the text has been significantly reduced so that only key information is included and re-formatted according to the EAU non-oncology template so that all Guidelines follow a similar format.

2013

All chapters were updated to include the latest data (published between January 2011 and October 2012).

2012

  • Literature has been assessed for all sections and updated if relevant.
  • New chapter on Methodology
  • 4.4.4.2 “Y chromosome: ‘gr/gr’ deletion” added
  • 6.4 “Basic considerations” for varicocele updated