Apply for use of EAU RF’s Castor database

EAU Research Foundation (EAU RF) supports a new registry infrastructure

The mission of the EAU Research Foundation (EAU RF) is to promote, facilitate and stimulate clinical and basic research in European urology. We set out to achieve this mission by acting as a bridge between urological centres, research organisations and the EAU. We are working in close collaboration with the EAU guidelines office (EAU GO), the EAU Section Office and with other sections within the EAU to identify and fill gaps of knowledge in the field of urology.

Today, there are many unmet needs in the field of urological research. At the same time, Europe as a platform, holds great potential for impactful investigations. In our vision, we strive towards a future, in which European urology research is abounding, relevant, high-quality, and yielded through a consolidated collaborative infrastructure.

In order to achieve our mission, we have decided to further support collection of important clinical data and to build new registries to serve as platforms for work on relevant scientific questions. By building a platform of prospectively collected clinical information and real-world data we will meet the requirements of producing high-quality research. The next generation of electronic medical records will –  in future – facilitate collection of clinical information and we need to be in the front-line of registry-based studies within the urological community.

EAU RF has now implemented a new electronic database management system (Castor EDC) that is validated and satisfies GDPR and EU research legislation. Castor EDC can be used by EAU Researchers when their research proposal is accepted after peer review. The research proposal will be defined into Castor EDC by one of the EAU RF project managers at the EAU Central Office in Arnhem where after Castor EDC can be used for the duration of the research project. Research project related responsibilities like protocol writing, EC submission, data management, statistical analysis, providing manpower for the conduct of the study, including scientific, regulatory and legal aspects is the responsibility of the researcher, the EAU Researchers group or -Institution. EAU RF can play an advisory role to fulfil such research proposal related responsibilities but cannot provide the researcher with financial incentives, manpower or support. If additional funding is available and you wish more help from EAU RF, we may be able to help you with specific research proposal related responsibilities. EAU RF has developed an application form to provide EAU RF and expert reviewers with the research proposal specifics.

Examples of currently accepted projects are:

  • eCORE Proposed by the the EAU section of Urolithiasis (EULIS)
    PI: Prof Selcuk Guven, Istanbul, Turkey
    Patient survey in patients with kidney stones to measure compliance to diet and/or medical treatment. Target is 1000 patients in 15-20 centers.
  • Changing future in Bladder cancer variants: the EAU-BRaVeRY (BladdeR Variants RegistrY).PIs: Prof Andrea Necchi, Istituto Nazionale dei Tumori, Milan and Prof A. Gallina Ospedale San Raffaele, Milan
    Project manager: Filippo Pederzoli, MD, Urological Research Institute, DiBit2, Scientific Institute San Raffaele
    A prospective, centralized, multicenter bladder cancer registry to study the prevalence and behavior of urothelial-variant histologies and non-urothelial histologies in muscle-invasive disease.
  • Prospective registry on Renal Cell Carcinoma (RCC) following the RECUR database (Frontier). Proposed by the RECUR consortium, currently including 15 sites in 9 European countries and with established RCC experts.
    PIs: Prof Axel Bex, London (GB), Dr Saeed Dabestani, Malmö (SE) and Dr Samra Turajlic, Francis Crick Institute, London (GB).
    Novel molecular biomarkers will be evaluated in a clinical setting to see whether more accurate prognostication can be obtained both in the localized and metastatic settings of RCC. The second goal of a prospective registry would be to determine the best follow-up protocol according established or novel risk stratification tools.

Please find The EAU RF Research Project Application Form for use of Castor here.

If you would like to get in touch with the EAU Research Foundation for any questions or suggestions, please send an e-mail to:

Prof Anders Bjartell MD PhD FEBU, Malmö (SE)
Chairman, EAU Research Foundation

Prof Arnulf Stenzl MD PhD Tubingen (DE)
Adjunct Secretary General Executive Member Science, EAU

Dr Wim P. J. Witjes MD PhD Arnhem (NL)
Scientific and Clinical Research Director, EAU Research Foundation