For the 2025 Non-neurogenic Female LUTS Guidelines new and relevant evidence was identified, collated and appraised through a structured assessment of the literature for all sections of the guidelines. Key changes include:

A new summary of evidence (SOE) in section 3.71 for pad tests.
New SOE and recommendations in section 4.1.4.1.2.1 for conservative management of OAB.
Summarized text in section 4.1.4.1.3 and an additional SOE with regards to urinary containment.
New SOE and recommendation in section 4.1.4.1.5.5 for behavioural and physical therapies.
A new recommendation for anticholinergic drugs in section 4.1.4.2.1.4.
A new section 4.1.4.2.6 on Saw palmetto extract.
A new SOE for detrusor myomectomy in section 4.1.4.3.4.4.
A new SOE for pelvic floor muscle training in section 4.2.4.1.3.7.
A new SOE and recommendations for electromagnetic stimulation and electroacupuncture in section 4.2.4.1.6.
A new recommendation in section 4.2.4.3.2.5.1 for mid-urethral slings and in section 4.2.4.3.2.6.1 for treatment of stress urinary incontinence.
A new section 4.3.3.3.2 on Mirabegron as well as a new SOE.
A new SOE in section 4.5.5.2.3.3 for surgical management of functional bladder out let obstruction.
Extensive update on the pharmacological management of Nocturia, including new SOE in section 4.6.4.3.
A new SOE and recommendation for detection of SUI in women with POP, in section 4.7.3.2.
A new recommendation for the classification of urinary fistula in section 4.8.2.1