The literature for the complete document has been assessed and updated, where relevant.

A text section has been added:

Section 7.3.3 - Salvage treatment in recurrent primary urethral carcinoma after surgery for primary treatment.

New recommendations have been added to:

Section 7.1.1 - Summary of evidence and guidelines for the treatment of primary urethral carcinoma in males.

Recommendation

LE

Strength rating

Ensure complete circumferential assessment of the proximal urethral margin if penis-preserving surgery is intended.

3

Strong

Section 7.3.5 - Summary of evidence and guidelines for multimodal treatment in advanced urethral carcinoma in both genders.

Recommendations

LE

Strength rating

Systemic therapy in advanced disease should be selected based upon histology of the tumour.

3

Strong

Offer salvage surgery or radiotherapy to patients with urethral recurrence after primary treatment.

3

Strong