The key changes and updates on the 2025 EAU guidelines on urological infections include the following:
- Introduction of a new UTI classification system. Changes are explained in detail in Section 3.1.
- Update of Section 3.4 on cystitis including the addition of a new Section 3.4.4 on non-antibiotic treatments for the management of cystitis.
- Update of the evidence and recommendations for immunomodulatory prophylaxis for recurrent UTIs in Section 3.5.3.3.2.
- Update of the evidence and recommendations in Section 3.7 addressing systematic UTIs.
- Update of the evidence in Sections 3.10 on urethritis and 3.12 on acute epididymitis.
- Introduction of a new Section, 3.15, on Herpes Simplex Virus (HSV).
- Update of the evidence and recommendations on prostate biopsy in Section 3.17.2.8.
- Update of the antibiotic dosages where applicable.